As of today, a cumulative total of 930 711 cases of COVID-19 have been identified with 8 789 identified since the last report.
| Province | Total cases for 21 December 2020 | Percentage total |
| Eastern Cape | 159767 | 17,2 |
| Free State | 60536 | 6,5 |
| Gauteng | 258202 | 27,7 |
| KwaZulu-Natal | 160261 | 17,2 |
| Limpopo | 20354 | 2,2 |
| Mpumalanga | 33335 | 3,6 |
| North West | 36801 | 4,0 |
| Northern Cape | 24250 | 2,6 |
| Western Cape | 177205 | 19,0 |
| Unknown | 0 | 0,0 |
| Total | 930711 | 100,0 |
A cumulative total of 6 176 683 tests have been conducted with 35 844 tests conducted since the last report
| Sector | Total tested | New tested | ||
| PRIVATE | 3 576 289 | 58% | 19 507 | 54% |
| PUBLIC | 2 600 394 | 42% | 16 337 | 46% |
| Total | 6 176 683 | 35 844 |
Regrettably, today we report 216 COVID-19 related deaths have been reported: Eastern Cape 97, Free State 4, Gauteng 16, Kwa-Zulu Natal 15 and Western Cape 84. This brings the total to 24 907 deaths.
Our recoveries now stand at 796 346.
| Province | Total Deaths | Total Recoveries | Active Cases |
| Eastern Cape | 6252 | 139 264 | 14 251 |
| Free State | 2131 | 53 947 | 4 458 |
| Gauteng | 5196 | 237 741 | 15 265 |
| KwaZulu-Natal | 3658 | 124 620 | 31 983 |
| Limpopo | 526 | 18 635 | 1 193 |
| Mpumalanga | 624 | 31 597 | 1 114 |
| North West | 571 | 34 116 | 2 114 |
| Northern Cape | 372 | 21 859 | 2 019 |
| Western Cape | 5577 | 134 567 | 37 061 |
| Total | 24 907 | 796 346 | 109 458 |
Dr Zwelini Mkhize
Minister of Health
